Domperidone: A Medication That Wears Many Hats
Like Mr. Rogers entering the room and changing his sweater and shoes, a medication that can cure more than one ailment is welcome in any home. Used orally, rectally or intravenously, prescription domperidone is most commonly used to suppress nausea and vomiting. Domperidone, the cheaper generic form of prescription Motilium, can also be a very friendly neighbour if you suffer from any of the following ailments.
If it's your guts that have you shaking your fist at the sky, domperidone has been found effective in the treatment of gastroparesis. Gastroparesis, also called delayed gastric emptying, is a disorder in which the stomach takes too long to empty its contents. Normally, the stomach contracts to move food down into the small intestine for digestion. The vagus nerve controls the movement of food from the stomach through the digestive tract.
Gastroparesis occurs when the vagus nerve is damaged and the muscles of the stomach and intestines do not work normally. Food then moves slowly or stops moving through the digestive tract. Domperidone aids by improving stomach emptying and decreasing nausea and vomiting to make this chronic condition more bearable. For the littlest member of the family, domperidone has also been proven effective for pediatric gastroesophageal reflux (infant vomiting).
For new Mamas having difficulties breastfeeding due to a lack of milk production, there is the option of store-bought formula. But if it's breast or bust, domperidone can come to the medical rescue. How it works is the hormone prolactin stimulates lactation in humans, and its release is inhibited by the dopamine secreted by the hypothalamus. Domperidone, by acting as an anti-dopaminergic, results in increased prolactin secretion, and thus promotes lactation. For women who want the best source of nutrients and the bonding that breast-feeding provides, domperidone can be a wonder drug.
Domperidone is also prescribed for treating nausea and vomiting associated with medications used to treat Parkinson's disease because, unlike medications like metoclopramide, domperidone does not cross the blood-brain barrier.
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